The NHS says it is life-threatening and can be hard to spot, while the UK Sepsis Trust says there are about 50,000 sepsis-related deaths in the UK each year.
"It's only me and my twin sister," says Becky Joyce. "How long can we keep going when the need is getting bigger and bigger?"
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Marieke Pepers says she gets her best ideas while out walking her dog
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Grandfather and father-of-three Steve O'Farrell, 67, from Bristol, said he had struggled with his weight throughout his adult life, and Mounjaro had been the only treatment to make a lasting difference.